Chloroquine-proguanil malaria prophylaxis

Discussion in 'Canada Drugs Online' started by ivaska, 12-Mar-2020.

  1. baks2008 Guest

    Chloroquine-proguanil malaria prophylaxis


    This type of malaria medication consists of two different drugs, one called chloroquine phosphate and one called proguanil hydrochloride, that are taken as two separate tablets but are packaged together. The two drugs are taken in combination to be more effective against malaria and as a form of malaria treatment, by inhibiting the reproduction of the parasites responsible for causing malaria.

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    Does chloroquine and proguanil protect against malaria? Although chloroquine is an antimalarial, it is often not sufficient for prophylaxis. Chloroquine used to be the antimalarial of choice and it was widely used for from 1947 onwards. As a result, the malaria parasites endemic to certain regions developed a resistance to chloroquine. Chloroquine, proguanil, mefloquine, and doxycycline are suppressive prophylactics. This means that they are only effective at killing the malaria parasite once it has entered the erythrocytic stage blood stage of its life cycle, and therefore have no effect until the liver stage is complete. Chloroquine proguanil medication is used to prevent and treat malaria. This type of malaria medication consists of two different drugs, one called chloroquine phosphate and one called proguanil hydrochloride, that are taken as two separate tablets but are packaged together.

    In some countries, chloroquine proguanil medication requires a prescription, and in other places it is available without a prescription, but it is recommended to consult a doctor before taking any malaria medication. Both these drugs can have serious side effects, especially when taken together, including itching, skin rash, stomach pain, bloody stool, and hair loss.

    Chloroquine-proguanil malaria prophylaxis

    Malaria - Chapter 4 - 2020 Yellow Book Travelers' Health., Malaria prophylaxis - Wikipedia

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  4. Malaria Information and Prophylaxis by Country; Country Areas with Malaria Drug Resistance 2 Malaria Species 3 Recommended Chemoprophylaxis 4 Key Information Needed and Helpful Links to Assess Need for Prophylaxis for Select Countries; Gabon All Chloroquine P. falciparum 90%, P. malariae, P. ovale, P. vivax 10% combined

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    Question Some of my pregnant patients wish to travel to malaria-endemic regions. Are there medications that can be used safely during pregnancy for malaria prophylaxis? Answer Pregnant women should avoid travel to malaria-endemic areas if possible. However, if travel cannot be avoided, measures to prevent mosquito bites, along with an effective. In The Travel and Tropical Medicine Manual Fifth Edition, 2017. Author recommendations For travelers to areas with known or potential chloroquine-resistent malaria with a predominance of Plasmodium falciparum or Plasmodium vivax, clinicians should prescribe any of the following malaria preventive drugs mefloquin, doxycycline, chloroquine-proguanil, or atovaquone-proguanil. Mefloquine, taken to prevent malaria may increase the risk of convulsions or fits when taken at the same time as chloroquine.  Levothyroxine thyroid medicine.  Medicines used to treat epilepsy, as chloroquine may reduce their effectiveness.

     
  5. sinol XenForo Moderator

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