Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Chloroquine and hiv Interactions between flecainide and hydroxychloroquine Hydroxychloroquine is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Hydroxychloroquine may also be used for purposes not listed in this medication. Hydroxychloroquine is used to prevent or treat malaria infections caused by mosquito bites. It does not work against certain types of malaria chloroquine-resistant. The United States Center for. Hydroxychloroquine is often prescribed as long-term therapy for many dermatologic indications, and it may have broader benefits e.g. preventing or improving thrombophilia associated with lupus erythematosus, neonatal lupus erythematosus, diabetes in rheumatoid arthritis and other connective tissue diseases, and as adjunctive therapy in some cancers. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Long term use of hydroxychloroquine Are Long-Term Chloroquine or Hydroxychloroquine Users Being., Hydroxychloroquine Oral Uses, Side Effects, Interactions. Chloroquine ovarian cancerChloroquine bioavailabilityDoes plaquenil work like anxiety medsStatistics about chloroquineMoa chloroquine Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis. Plaquenil is the brand name of hydroxychloroquine, a drug used to prevent or treat malaria. Plaquenil is also used for long-term treatment of autoimmune diseases such as rheumatoid arthritis RA and systemic lupus erythmatosis. Long-Term Side Effects of Plaquenil for Rheumatoid.. How Safe Is Long-Term Hydroxychloroquine?. Hydroxychloroquine Oral Route Side Effects - Mayo Clinic. Hydroxychloroquine oral tablet is available as a brand-name drug and a generic drug. Brand name Plaquenil. Hydroxychloroquine comes only as a tablet you take by mouth. Hydroxychloroquine is used to treat malaria, lupus erythematosus, and rheumatoid arthritis. Long-term use and high doses of hydroxychloroquine are risk factors for the development of cardiomyopathy. Cardiac failure, conduction disorders including QT prolongation and Torsades de Pointes and sudden cardiac death are consequences of the cardiomyopathy. MADRID — Long-term use of hydroxychloroquine was associated with reduced cardiovascular risks in a cohort of patients with systemic lupus erythematosus, according to findings presented at the.