This information should not take the place of medical care and advice from your healthcare providers. Hydroxychloroquine is a medication used to prevent and treat malaria and to treat autoimmune conditions such as rheumatoid arthritis or lupus. Plaquenil for urticaria Aralen Today, Plaquenil and other antimalarials are also used to treat and help prevent symptoms caused by certain autoimmune diseases such as rheumatoid arthritis RA, systemic lupus erythematosus, and discoid lupus, even though these diseases are not caused by malaria parasites. Hydroxychloroquine Use in Lupus Patients during Pregnancy Is Associated with Longer Pregnancy Duration in Preterm Births. 1Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht, Netherlands. 2Department of Gynecology and Obstetrics, University Medical Center Utrecht, Utrecht, Netherlands. Posts RE Plaquenil Hydroxychloroquine during pregnancy Posted on Jan 9, 2015 at pm I'm six weeks pregnant and jumped in this convo because I had just read a study where in some t ypes of APA's, Lovenox and Bany Aspirin are not enough. I've had two healthy children followed by three second trimester, unexplained losses. For more information on rheumatoid arthritis or lupus in pregnancy please see the Mother To Baby fact sheet on those topics at: https://mothertobaby.org/fact-sheets/rheumatoid-arthritis/pdf or https://mothertobaby.org/fact-sheets/lupus-pregnancy/pdf/. Hydroxychloroquine is sold under several brand names, including Plaquenil®. Plaquenil use during pregnancy Hydroxychloroquine Side Effects, Dosage, Uses, and More, Hydroxychloroquine Use in Lupus Patients during Pregnancy. Hydroxychloroquine should you take if you are anemic Hydroxychloroquine Plaquenil, chloroquine Aralen, and quinacrine Atabrine are medications that were originally used to prevent or treat malaria. However, during World War II it was also found that these medications were effective in treating the symptoms of lupus. Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus Center. Plaquenil Hydroxychloroquine during pregnancy.. Plaquenil - Side Effects, Uses, Dosage, Overdose.. Use of this drug during pregnancy should be avoided except in the suppression or treatment of malaria. -This drug crosses the placenta. -Therapeutic doses of 4-aminoquinolines have been associated with central nervous system damage, including ototoxicity auditory and vestibular toxicity, congenital deafness, retinal hemorrhages and abnormal retinal pigmentation. How to use Plaquenil. Hydroxychloroquine is usually taken with food or milk to prevent stomach upset. The dosage and length of treatment are based on your medical condition and response to therapy. In children, dosage is also based on weight. Hydroxychloroquine and prednisone are considered safe during pregnancy. Methotrexate and cyclophosphamide Cytoxan should not be used in pregnancy and should be discontinued for at least a.