If in about 6 to 8 weeks you aren't seeing the slightest change, or don't feel it is enough, let your doc know, and he can adjust. Plaquenil is used to inhibit disease progression - most of us are started on it immediately and need to remain on it long-term. Generally a rheumy will then choose one of these three; Imuran, Cellcept, or MTX to inhibit the over-active autoimmune system that is Lupus. Others here have gotten great results from either Imuran or MTX. I see that in June you were asking about MTX (Methotrexate). I found that following my Dr's instinct/experience/training gave me good results. Hydroxychloroquine sulfate advers reactions What can plaquenil do to you if taken wrong Prophylaxis of malaria chloroquine I have lupus and aps and due to a flare that's lasted 10 months the rheumatologist started me on azathioprine. I started on 50mg twice daily with little effect so it was increased to 3 times a day. Then my liver enzymes shot up so had to stop the azathioprine was gutted as it had just started to make me feel better! Once lupus has been diagnosed, your doctor will develop a treatment plan for you based on your age, sex, health, symptoms, and lifestyle. In developing your treatment plan, your doctor has several goals 1 Reduce inflammation caused by the disease Suppress immune system abnormalities that are responsible for tissue. Compare Azathioprine vs. Plaquenil, which is better for uses like Lupus, RA and Arthritis. Compare head-to-head ratings, side effects, warnings, dosages, interactions and patient reviews. Patients rated Plaquenil 3.7/5 over Azathioprine 3/5 in overall satisfaction. So my Dr moved on to Cellcept, which was a miracle medication for me. There are no clear guidelines that recommend starting with one of these over the others -- and it's hit-and-miss which one will work best for any individual patient. The Dr knows exactly how your individual manifestation of the disease is presenting, what has already been tried, how you reacted to it... She choose Imuran over Methotrexate because I enjoy red wine on the weekends. How does azathioprine work with plaquenil for lupus Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus, Lupus Treatment Options Hydroxychloroquine mechanism of action in lupus Even though Imuran is effective in treating serious lupus symptoms, long term use of this medication does increase the risk of developing cancer. Your doctor can speak with you about this risk and any other concerns you may have. She/he will work with you to minimize the side effects of your medications while also maximizing the benefits. Treating Lupus with Immunosuppressive Medications Johns.. Compare Azathioprine vs Plaquenil - Comprehensive Analysis.. Lupus remission Lupus Foundation of America. Used for pain, rashes, and lung inflammation. Most commonly used is hydroxychloroquine Plaquenil. This drug, however, can cause headaches, weight loss, and stomach pain. Other medications include B-lymphocyte specific inhibitors belimumab and immunosuppressants methotrexate, azathioprine, cyclophosphamide. Disease Outlook Fortunately, cellcept mycophenolate does not affect the liver like azathioprine does. It will take anywhere from 8-12 weeks to work, BUT it also can cause side effects, one of which can be raising your blood sugar, so you must be monitored closely with frequent blood tests. Azathioprine Dose Increase. This autumn, I had a serious episode where I fell very ill, and I know that the people I work with my work friends knew, but when I came back to work, no-one asked if I was ok. No-one mentioned it at all. I received my official diagnosis of Lupus this week, and while I’m still figuring out how I feel.