Occasionally, weight gain can be a symptom of The older type of antihistamines do tend to lead to weight gain. In fact, periactin (cyproheptadine hydrochloride) was often used to induce weight gain at one time. Plaquenil monitoring Best way to take plaquenil Plaquenil is a slow-acting drug, meaning that it can take up to 6 months to experience the full benefits of this medication, but it is possible for symptoms to improve in as few as 1 or 2 months. Plaquenil and other antimalarials are the key to controlling lupus long-term, and some lupus patients may be on Plaquenil for the rest of their lives. Lynwood, I can't answer your question about weight gain or loss on plaquenil but I did go off plaquenil a few months ago and haven't been the same since. I regret the decision which had I made because I'd felt pretty well for quite some time and was doing my best to slowly get off as many meds as possible. Potential Plaquenil side effects include nightmares, weight loss, and diarrhea. This eMedTV resource provides a list of other possible side effects of Plaquenil, including serious ones that require medical attention such as hearing loss or seizures. The only weigh to increase muscle tone and/or mass is with weight (resistance) training. If there is another reason that you wish to gain weight, ask again ... Read more See 1 more doctor answer Any vigorous exercise will do; weight training may be more effecive. Foods to help w healthy weight gain: almonds, cashews, pecans, sunflower seeds, flax seeds, walnuts, hummus, avocados, granola, trail mix, dried fruits, extra virgin olive oil ; canola oil. Since Hydroxyzine is an older antihistamine, the answer is yes for some people. Read more See 1 more doctor answer If you are a thin person and just want to gain weight, what you want is muscle not fat. So be delighted that you are not a part of the obesity epidemic and go a gym and get toned muscles. Does plaquenil weight gain Lupus Symptoms Johns Hopkins Lupus Center, Plaquenil & Weight Gain/Loss - Hydroxychloroquine muscle toxicityNexium and plaquenilVitamin c and plaquenilDoes plaquenil help with ms Corneal changes including edema and opacities can be symptomless or may cause disturbances such as haloes, blurring of vision or photophobia. They may be transient and are reversible when therapy is discontinued.-Maculopathies and macular degeneration can occur from 3 months to several years of exposure to this drug and may be irreversible. Plaquenil Side Effects Common, Severe, Long Term -. Plaquenil Side Effects - Antibiotics Home Page. Medrol, Plaquenil and weight gain - Sclero Forums MAIN.. According to the Mayo Clinic, the daily dose for RA is based on body weight; the dose is 2.9mg per pound 1. This means many people taking Plaquenil for RA are taking a dose of 400mg a day or higher. Pigment deposits in the retina can cause vision changes, according to Steven Ofner, M. D. of Eugene Oregon Eye Care. Doctors give unbiased, trusted information on whether Plaquenil can cause or treat Weight Gain Dr. Valdez on hydroxychloroquine and weight gain Depression can cause weight gain and loss, but alopecia not a common sign of depression. Dosage for Plaquenil. The adult dose of Plaquenil to suppress malaria is 400 mg on the same day each week. The pediatric weekly suppressive dosage is 5 mg/kg of body weight. The adult dose of Plaquenil to treat an acute attack of malaria is an initial dose of 800 mg followed by 400 mg in six to eight hours and 400 mg for two more days.