She suffered from Sjogren syndrome and inflammatory arthritis and was currently treated with prednisone and methotrexate. She was previously treated with hydroxychloroquine (Plaquenil) 200mg bid (6.5mg/kg) for 10 years, which was stopped one year prior to presentation. Plaquenil lymphoma Difference between chloroquine and hydroxychloroquine Recommendations on Screening for Chloroquine and Hydroxychloroquine Retinopathy Retinal toxicity from chloroquine CQ and its analogue, hydroxychloroquine HCQ, has been recognized for many years. Chloroquine toxicity remains a problem in many parts of the world, but is seen less frequently in the United States where the drug largely has been replaced by HCQ. Visual screening tests can be performed. If you are pregnant, considering becoming pregnant, or lactating, please discuss this with your doctor before taking this medication. However, hydroxychloroquine has been shown to be safe during pregnancy and breast feeding. Hydroxychloroquine typically is very well tolerated. Serious side effects are rare. Macular Society Eye screening for patients taking hydroxychloroquine Hydroxychloroquine is a medication used to treat several conditions including rheumatoid arthritis, systemic lupus erythematosus, some skin conditions especially photosensitive ones and others that involve inflammation. It was previously used in the treatment and Review of systems: Blurred vision, halos, dry eye, dry mouth, gastroesophageal reflux, joint pain Pupils: Reactive to light in each eye from 5 mm in the dark to 2 mm in the light. Extraocular movements: Full, both eyes (OU) Confrontation visual fields: Full OU Intra-ocular pressure The optic nerves appeared healthy with a 0.3 cup-to-disc ratio. Past Ocular History: None Medical History: Sjogren syndrome and inflammatory arthritis, supraventricular tachycardia, anxiety, depression, peptic ulcer disease Medications: prednisone, methotrexate, amitriptyline, ranitidine, estradiol, tizanidine, diltiazem, Restasis Allergies: codeine, droperidol Family History: heart disease, arthritis, cancer Social History: occasional alcohol but no tobacco or intravenous drug use. Fang and hydroxychloroquine screening Comparison of the effects of hydroxychloroquine and., PATIENT FACT SHEET Hydroxychloroquine Plaquenil Chloroquine phosphate for aquariumMetabolic fate of chloroquineChloroquine sle New Screening Guidelines for Hydroxychloroquine Toxicity Experts explain their role in clinical practice. Stephen G. Schwartz, MD, MBA • William F. Mieler, MD. Hydroxychloroquine Plaquenil, Sanofi-Aventis remains widely used in the treatment of various rheumatologic disorders. New Screening Guidelines for Hydroxychloroquine Toxicity. Eye screening for patients taking hydroxychloroquine Plaquenil. Hydroxychloroquine and Chloroquine Retinopathy.. Screening interval has also been updated. All patients will need a baseline screening before or within 1 year of initiation of hydroxychloroquine. The baseline examination includes a fundus. The new guideline on screening for hydroxychloroquine and chloroquine retinopathy is written in response to evidence from the United States that shows that hydroxychloroquine retinopathy is more common than previously recognised. Implementation of the guideline’s recommendations will prevent iatrogenic visual loss. The new guideline also makes recommendations regarding the techniques and. Guidelines on screening for retinopathy associated with hydroxychloroquine toxicity were initially published by the Academy in 2002. These guidelines were updated in February of this year, given the emergence of more sensitive diagnostic techniques and the recognition that risk of toxicity from years of hydroxychloroquine use is greater than.