Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Plaquenil toxicity monitored with Can you gain weight on plaquenil Plaquenil ara How does h-chloroquine work for rheumatoid arthritis Background Hydroxychloroquine HCQ, one of the disease-modifying antirheumatic drugs, may lead to an inhibition of autophagy. Autophagy, an intracellular self-defense mechanism for the lysosomal degradation of cytoplasmic components such as damaged organelles, plays a role in protecting against neoplasm growth but is also vital for cancer cells due to an increased intracellular metabolic waste. Hydroxychloroquine is in a class of drugs called antimalarials. It is used to prevent and treat acute attacks of malaria. It is also used to treat discoid or systemic lupus erythematosus and rheumatoid arthritis in patients whose symptoms have not improved with other treatments. This trial is looking at adding a drug called hydroxychloroquine HCQ to radiotherapy as treatment for a type of brain tumour called a high grade glioma in people aged 70 or over. The trial is supported by Cancer Research UK. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. Hydroxychloroquine plaquenil cancer Plaquenil Uses, Dosage & Side Effects -, Hydroxychloroquine MedlinePlus Drug Information Hydroquinone plaquenilHydroxychloroquine and liver cirrhosisAtorvaquone vs chloroquineHydroxychloroquine drug classChloroquine expired side effects If you have any questions, contact a member of your healthcare team directly. If you're a patient at MSK and you need to reach a provider after pm, during the weekend, or on a holiday, call 212-639-2000. Hydroxychloroquine - Memorial Sloan Kettering Cancer Center. A trial of hydroxychloroquine HCQ. - Cancer Research UK. Risk of Nonmelanoma Skin Cancer Associated With the Use of.. This phase I / II trial studies the side effects and best dose of hydroxychloroquine when given together with palbociclib and letrozole before surgery in treating participants with estrogen receptor positive, HER2 negative breast cancer. Hydroxychloroquine is a substance that decreases immune responses in the body. Hydroxychloroquine inhibits autophagy, a prosurvival process that breast cancer cells induce and that antiestrogens can stimulate. Whether interfering with this process can enhance breast cancer therapy remains unknown. Researchers say a drug commonly used to treat malaria and rheumatoid arthritis has also proved effective in treating some aggressive cancers. When scientists administered hydroxychloroquine, an anti-malarial drug, together with known cancer drugs, they found it stopped the growth of cancerous tumors in two-thirds of the patients.