The clinical trials on this list are studying Hydroxychloroquine. NCI’s basic information about clinical trials explains the types and phases of trials and how they are carried out. Clinical trials look at new ways to prevent, detect, or treat disease. Curvilinear bodies hydroxychloroquine cardiomyopathy Plaquenil and risperdal Antimalarial drugs chloroquine and hydroxychloroquine could find another use as cancer treatments, according to a new clinical study published in ecancermedicalscience. Methotrexate is often the first treatment given to people with RA. But it could make you more likely to get some cancers, especially skin cancer. One study found methotrexate may be tied to melanoma, non-Hodgkin's lymphoma, and lung cancer. Interstitial lung disease is found among people who take Plaquenil, especially for people who are female, 50-59 old, have been taking the drug for 5 - 10 years, also take medication Enbrel, and have Pain. Talk to your doctor for help in deciding if one is right for you. You may want to think about taking part in a clinical trial. Hydroxychloroquine and lung cancer Hydroxychloroquine + Carboplatin, Paclitaxel and Bevacizumab in Non., RA Drugs and Cancer What’s the Link? Can chloroquine treat diarrheaChloroquine side effects dreamsHydroxychloroquine other namesPlaquenil chronic urticaria Autophagy and cancer. A large body of evidence suggests that the relationship between autophagy and cancer is complex.42, 43 On the one hand, autophagy appears to inhibit malignant transformation, reflecting its capability to limit the accumulation of potentially oncogenic entities like depolarized mitochondria which overproduce potentially genotoxic reactive oxygen species, ROS. Chloroquine and hydroxychloroquine for cancer therapy. Will you have Interstitial lung disease with Plaquenil.. Hydroxychloroquine - Memorial Sloan Kettering Cancer Center. Hydroxychloroquine Plaquenil is also a disease-modifying anti-rheumatic drug DMARD used to treat both acute and chronic rheumatoid arthritis, systemic lupus erythematosus, and discoid lupus erythematosus. Rheumatoid Arthritis Drug Linked to Cancer. Nov. 16, 2004 -- For people with rheumatoid arthritis, methotrexate is the treatment of choice in reducing pain and inflammation. But there's evidence the drug can activate a virus that can increase the risk of lymphoma and similar cancers in some patients. One of the treatments for small cell lung cancer SCLC is chemotherapy. The chemotherapy most often used is a carboplatin and etoposide. This is a standard treatment. Recent research shows that a drug called hydroxychloroquine HCQ might help chemotherapy work better.