These interactions are explained in the Proton Pump Inhibitors article, which is part of the extensive Drug Interactions section of our website (where you can look up interaction for other drugs you may be taking). Be sure to also read about magnesium depletion which can occur with these drugs in the Magnesium Supplements Review. Plaquenil and hungry Hydroxychloroquine sarcoidosis Rheumatoid arthritis methotrexate versus hydroxychloroquine Michael marmor plaquenil dosage Summary Drug interactions are reported among people who take Omeprazole and Hydroxychloroquine sulfate together. This study is created by eHealthMe based on reports of 1,041 people who take Omeprazole and Hydroxychloroquine sulfate from Food and Drug Administration FDA, and is updated regularly. If taken in combination with these drugs, it will actually increase your body’s production of stomach acid. This can cause nausea, bloating and stomach pain and can also damage your esophagus. Drugs that reduce stomach acid include Cimetidine Tagamet, Famotidine Pepcid, Ranitidine Zantac and Omeprazole. Omeprazole Prilosec, Nexium, and other proton pump inhibitor drugs can be affected by taking supplements, and can affect your ability to absorb certain vitamins and minerals. St. John's wort, for example, should not be taken with these drugs. Also see the Encyclopedia article about Gastroesophageal Reflux Disease (GERD) for other proposed treatments for this condition, including deglycyrrhizinated licorice, marshmallow, slippery elm and others, as well as our CL Answer about supplements for indigestion and heartburn. I have GI problems and wonder if I should avoid turmeric and curcumin? And, if you take a calcium supplement, read in the Calcium Supplements Review how certain forms of calcium may be preferable if you are taking these drugs. Omeprazole and plaquenil UpToDate, Don’t EVER use turmeric if you’re on any of the following. Trialnet hydroxychloroquineDoes plaquenil effect healing after surgeryPlaquenil forlimited sclera derma Proton pump inhibitor PPI interactions can occur with at least 290 medicines. These other drugs come in both brand name and generic versions. They add up to more than 1,800 different products. At least 20 of these drugs can cause a severe reaction if taken with certain PPIs. Proton Pump Inhibitor PPI Interactions Drugs, Foods.. Supplements to Avoid While Taking a Proton Pump Inhibitor.. Is it safe to take Linzess 145mcg & Omeprazole 40mg.. They also may be accompanied by other medications such as misoprostol Cytotec®, omeprazole Prilosec®, lanzoprazole Prevacid® and others. You may need a prescription for these medications. Long term plaquenil users on high doses will need to get check-ups for eye health regularly to prevent retinal toxicity from long-term use. Hydroxychloroquine with omeprazole. dillydally1. I take my omeprazole before breakfast ideally at least 1/2 hour and hydroxy at night after my main meal but then. Plaquenil is very effective for the symptoms of achiness and fatigue. However, there might be a price to pay in terms of retinal toxicity especially after taking it for as long as you have. Given that the alopecia had developed while you were on the plaquenil, it's not clear that going back on it will help that symptom much.