In the last six months my hearing in my good ear (I'm deaf in the left) has gotten worse in 7 out of 9 frequencies. At this rate I'll be completly deaf in a few years. It seems my current meds aren't doing the job but I hate to go to something stronger. Just out of curousity do you live in the mountains (as your screen name implies) If so, do you live in Colorado? I am not in the mountains but live on the front range, just outside of Boulder. I see the rheumy next week and I'm wondering if he's going to change my meds (Imuran and Plaquenil). No one know for sure if the deafness in my left ear is from the lupus, but with the right ear going now, I need to get as much info as I can. I haven;t heard much about hearing loss in lupus, so I looked it up. Lupylisa Hearing loss is more strongly associated with Sjogren's than with lupus or RA, but can happen. Plaquenil side effects tinnitus Plaquenil and chronic fatigue syndrome Plaquenil and stomach problems Hydroxychloroquine hydroxyzine interaxtion Audiometry test showed moderate to severe neuronal hearing loss and reduced speech recognition in both ears of the patient. With suspicion of hydroxychloroquine-induced hearing loss, this drug was discontinued. After 2 months of hydroxychloroquine discontinuation, his audiometry findings were improved. The plaquenil should definitely be out of your system by now. There is something called autoimmune inner ear disease that my ENT mentioned to me that I may or may not have my rheumy said no, it's too rare. Some of the symptoms are tinnitus and high frequency hearing loss of unknown cause. Hearing Loss is #71 concern in Plaquenil discussions. Plaquenil is an arthritis medication and an anti infectious agent. Uses Plaquenil is prescribed for Lupus, RA, Sjogren's Syndrome and Joint Pain and is mostly mentioned together with these indications. Because I have Sjogren's my rheumatologist thought it was more likely the disease than the medication, and kept me on Plaquenil, but others may have a different response. Any information and personal experiences you can share are welcome. I recall that Plaquenil is associated with hearing loss so your doc has to consider whether it's (a) totally unrelated to either, (b) related to your lupus, (c) related to your medications, or (d) a combination of both. Can plaquenil cause loss of hearing Plaquenil & Tinnitus Lupus Forums at The Lupus Site, Plaquenil and tinnitus DailyStrength Plaquenil side effects can you drink alcohol Hydroxychloroquine and hearing loss Introduction Hydroxychloroquine Plaquenil® is an antimalarial agent which is approved for rheumatoid arthritis, systemic lupus erythematosis, discoid lupus erythematosis, prophylaxis and treatment of acute malaria, and photodermatosis 1. In the Netherlands it has been approved since 1966. Hydroxychloroquine and hearing loss. Can Plaquenil cause Hearing Loss? - Page 2. When to Report Reactions to Plaquenil. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine I lost my hearing completely and permanently on one side whilst I was taking plaquenil. I don't know if it played a part but have refused it ever since that event. You can't hear in the same way with just one ear, but at least I still have one working ear. I had had perfect hearing in both ears prior to my sudden loss. Find information about common, infrequent and rare side effects of Plaquenil Oral.