It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. What autoimmune diseases does does plaquenil treat Can plaquenil cause hearing loss I can only tolerate one 200mg dose of plaquenil a day. I allergic to sulfa, and the full does causes my skin to break out in an itchy burning rash from scalp to toes, and everywhere in between. So, I do not have stomach issues, probably because of that. However, the methotrexate does cause some intestinal distress the following day. I am very familiar with Plaquenil, and Plaq does cause some tummy discomfort at the start. It can cause loss of appetite, diarrhea, and accompanying gas and intestinal noises. You can get some OC. Anyone have stomach pain after taking their plaquenil? I took my first dosage on Sunday and my stomach hurt so bad I could hardly stand it. I drank milk but it still hurt. Now I'm scared to take any more. I want to feel better but not at that cost. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Plaquenil and stomach issues Plaquenil -, Stomache Gas from Plaquenil or Gabapentin" Lupus Community. Pregnant plaquenil low plateltsSymptoms of hydroxychloroquine Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Although not all of these side effects may occur, if they do occur. Plaquenil Side Effects Common, Severe, Long Term -. Plaquenil and stomach pain DailyStrength. Long-Term Side Effects of Plaquenil for Rheumatoid.. In summary Plaquenil isn't causing tyour new problems. It probably caused only the nausea, diarrhea, stomach cramps, and intense vertigo. BTW 100 mg daily may reduce side effects, but this low dosage also greatly annihilates its positive effects. 100 mg are a drop maybe two. on a hot stone Re Plaquenil stomach issues Reply #5 on December 22, 2011, PM I took it for a week - one day at 400mg, reduced it to 200mg and was really ill with bad diarrhoea. Re Plaquenil and stomach issues. I don't plan on stopping the meds, I can tell you that, but I do have to call the dr today. Last night, I had a little treat and then about 2 oz of milk to wash it down.