It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Plaquenil cumulative dose Weight gain while using plaquenil Non-adherence to lupus nephritis treatment is the most important factor for non-remission or renal relapses. Hydroxychloroquine HCQ is currently recommended long term for all patients with SLE provided no contraindications exist. Despite all these benefits, hydroxychloroquine is too often still regarded as a second-line treatment, as we see from major randomised trials in which only about 50% of patients are treated with hydroxychloroquine, and even more strikingly from the absence of any mention of hydroxychloroquine in important studies. Treatment works well to control lupus nephritis, so you may not have complications. Between 10 to 30 percent of people who have lupus nephritis develop kidney failure. 6 Learn more about what happens if your kidneys fail. The most severe form of lupus nephritis, called diffuse proliferative nephritis, can cause scars to form in the kidneys. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis (or juvenile idiopathic arthritis) and other autoimmune diseases. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Plaquenil and nephritis Treating Lupus with Anti-Malarial Drugs Johns Hopkins., Hydroxychloroquine in systemic lupus erythematosus - The Lancet Plaquenil drug interactions side effectsChloroquine sp Plaquenil hydroxychloroquine belongs to a group of medicines called quinolines. Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Plaquenil Uses, Dosage & Side Effects -. Lupus and Kidney Disease Lupus Nephritis NIDDK. A Long-Term Study of Hydroxychloroquine Withdrawal on Exacerbations in.. Lupus nephritis is found among people who take Prednisone and Plaquenil, especially for people who are female, 20-29 old, have been taking the drugs for 5 - 10 years, also take medication Cellcept, and have Pain. This review analyzes which people have Lupus nephritis with Prednisone and Plaquenil. I have Lupus Nephritis and have had it for almost 12 years now. I strongly suggest you get tested for it because it sounds like that's what you may have, especially with protein in your urine. Better to be safe than sorry. I also take Plaquenil but it's stictly for my joints, all of my other medications are for my kidney function. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as.