Pattern of Retinopathy: Although the locus of toxic damage is parafoveal in many eyes, Asian patients often show an extramacular pattern of damage. Dose: We recommend a maximum daily HCQ use of 5.0 mg/kg real weight, which correlates better with risk than ideal weight. Hydroxychloroquine sulfate tablets usp 200 mg uses Plaquenil and blood pressure Dizziness on plaquenil Baseline Screening. Within first year of use. Visual fields and SD OCT if maculopathy is present. Annual Screening. Begin after 5 years of use but sooner if presence of major risk factors. Both HVF 10-2 and SD-OCT; optional testing as needed mfERG and/or FAF Mar 01, 2011 New Screening Guidelines for Hydroxychloroquine Toxicity Experts explain their role in clinical practice. Stephen G. Schwartz, MD, MBA • William F. Mieler, MD. Hydroxychloroquine Plaquenil, Sanofi-Aventis remains widely used in the treatment of various rheumatologic disorders. For years, eye doctors have relied on threshold visual field testing to detect functional vision changes with plaquenil use, rarely finding any signs of toxicity except in advanced cases where vision symptoms are already manifest. Risk of Toxicity: The risk of toxicity is dependent on daily dose and duration of use. There are no similar demographic data for CQ, but dose comparisons in older literature suggest using 2.3 mg/kg real weight. Plaquenil visual field screening How Do Ophthalmologists Look for Plaquenil Damage? - American., New Screening Guidelines for Hydroxychloroquine Toxicity Hydroxychloroquine side effects acneChloroquine for malaria prophylaxisMultifocal erg plaquenil toxicity It has become fairly common practice for most rheumatologists to recommend that patients being treated with hydroxychloroquine be seen for formal visual field evaluation once or twice a year to monitor for retinal toxicity. The previous AAO guideline recommended screening every 12 months. My Take on New Ocular Screening Guidelines for Plaquenil.. Plaquenil-Induced Toxic Maculopathy - Decision-Maker PLUS. Plaquenil - FDA prescribing information, side effects and uses. Apr 20, 2011 Subjective testing of the central visual field was recommended to uncover early functional changes associated with paracentral scotomas. Paracentral scotomas have been reported prior to the associated maculopathy, so an amsler grid test or central 10-2 visual field perimetry was recommended. 2,5 This test can help find if blind spots have developed in your field of vision. OCT imaging This test makes a detailed, three-dimensional image of your eye. Your ophthalmologist can use this image to look for early retinal damage. Multifocal ERG This test looks at cells in the retina called rods and cones. The test measures how well these. Nov 18, 2011 The 10-2 white test was felt by the authors to be the most reproducible and easiest to interpret. Although visual field defects in HCQ toxicity can be highly variable in terms of the depth of defect, all our patients showed a similar pattern on 10-2 white, with the same areas affected.